Martial scored his 23rd goal for United in all competitions this season against LASK Linz in Wednesday's Europa League last-16 victory.
The three Premier League and three La Liga clubs in the last eight avoided each other, with Manchester City up against Atletico Madrid and Liverpool to face Portuguese side Benfica.
Sheffield United lost their High Court action on Friday when they were refused leave to appeal against the Premier League arbitration panel's decision on the Carlos Tevez affair.
Liverpool moved into the Champions League qualifying spots after a 3-0 win at Burnley on Wednesday took them above Leicester City and into fourth place with one round of Premier League matches remaining.
Images from the English Premier League matches played on Saturday.
ManchesterCity manager Pep Guardiola has expressed doubts over whether Manchester United can challenge for the Premier League title but believes they have a realistic chance of finishing in the top four.
Chelsea's 0-0 home draw with second-placed United ensured Thomas Tuchel is still undefeated in nine games since replacing Frank Lampard, but it meant they failed to dislodge fourth-placed West Ham United who became Manchester City's 20th successive victims in all competitions on Saturday.
Rediff.com brings a preview of the main matches coming up this weekend in the English Premier League.
A summary of Saturday's action in the Premier League.
Ronaldo answered his critics five minutes after halftime with a superb finish
A summary of Saturday's action in the English Premier League.
IMAGES from the EPL matches played on Wednesday
Chelsea lost their 100 per cent Premier League record when London rivals West Ham United held them to a 0-0 draw on Sunday.
The world of sport reacted to the death of Queen Elizabeth on Thursday with a raft of cancellations across cricket, golf, rugby and cycling, while others paid tribute by holding a minute's silence.
Wayne Rooney's return for Manchester United after injury has been delayed with manager Alex Ferguson saying the striker may be sidelined for a further two weeks.
Chelsea's fiery Spain striker Diego Costa snatched a last-minute goal to secure a 2-1 home win over West Ham United and hand new manager Antonio Conte a winning start to his Premier League career on Monday. The bearded Costa collected a header from new signing Michy Batshuayi and thumped it low beyond West Ham goalkeeper Adrian's outstretched right hand to claim the points.
Erling Haaland's double put Manchester City within touching distance of an unprecedented fourth successive Premier League title
Manchester United stretched their unbeaten run to 11 games in all competitions after Daley Blind, in-form striker Zlatan Ibrahimovic and substitute Henrik Mkhitaryan gave them a 3-1 home win over Sunderland on Monday. Left back Blind fired United ahead with a crisp 39th-minute shot after Ibrahimovic teed him up perfectly. The towering Swede doubled the lead with a clinical 82nd-minute finish for his 17th goal of the season. Fit-again Mkhitaryan put the icing on the cake with a spectacular backheel effort after a sharp Ibrahimovic cross from the right, although television replays suggested the Armenian was marginally offside. Striker Fabio Borini gave Sunderland fans something to cheer with a dipping late volley.
Ronaldo enjoyed a dream first appearance on his return to the club, scoring two goals in the 4-1 home victory over Newcastle United.
Arsenal visit Liverpool looking for a first league win at Anfield since 2003. Defeat for Arsene Wenger's side will move seventh-placed Liverpool within a point of them, having played a game more.
Liverpool continued their relentless march to a first English title in 30 years, easing to a 2-0 victory at West Ham United on Wednesday to move 19 points clear at the Premier League summit. Mohamed Salah fired them ahead from the penalty spot in the first half and Alex Oxlade-Chamberlain doubled their advantage early in the second to wrap up a remarkable 23rd win from 24 games this season and stretch their unbeaten league run to 40.
The schedule of matches in the English Premier League between Saturday, September 26 and Monday, September 28.
Jose Mourinho was purring like a cat that had devoured the leftovers from Christmas dinner but it did not stop him showing his professional claws after his Chelsea side eased past West Ham United 2-0 on Friday.
Champions Manchester United's hopes of retaining their English Premier League title suffered another major setback on Saturday when they were beaten 1-0 at Old Trafford by a composed Newcastle United.
Phil Foden struck twice as Manchester City stepped up their bid for a fourth Premier League crown in a row with a ruthless 4-0 victory at Brighton & Hove Albion on Thursday.
Chelsea manager Maurizio Sarri said having Eden Hazard in such unstoppable form makes winning "easy" but appears almost resigned to losing him.
Match-by-match facts and statistics ahead of the first round of Premier League fixtures from August 5-7 (all times IST).
United down Newcastle after Saints stun Chelsea on a dramatic night in the English Premier League.
Steven Bergwijn scored twice in stoppage time as Tottenham Hotspur stunned Leicester City and pulled off a remarkable 3-2 victory in the Premier League on Wednesday.
Images from the English Premier League matches played on Saturday.
Liverpool hammered Sparta Prague 6-1 on Thursday to storm into the Europa League quarter-finals 11-2 on aggregate.
IMAGES from the English Premier League matches played on Saturday
West Brom, relegated from the Premier League last season, made 11 changes from the side that won at the weekend in the Championship and had five players -- including goalkeeper Alex Palmer -- making their debuts.
Manchester City stayed ahead of age-old local rivals Manchester United at the top of the Premier League on Saturday with a deserved 1-0 win away to champions Chelsea.
Images from Saturday's action in the Premier League.
Arsenal suffered another painful Premier League defeat as Swansea City capitalised on some glaring errors to win 3-1 on Tuesday, boosting their survival hopes and denting the visitors' top four chances.
Manchester United continued their perfect start to the Premier League season by crushing Swansea City 4-0 with three late goals in four minutes.
Champions Leicester City will begin their Premier League title defence with a trip to newly promoted Hull City on August 13, according to the 2016-17 fixtures released on Wednesday.
Manchester City set a new top-flight record of 15 consecutive wins as their seemingly unstoppable march towards the English Premier League title continued with a 4-0 romp at bottom club Swansea City.